A critical challenge in understanding the intricate programs underlying the development, assembly, function, and dysfunction of the human brain is the lack of direct access to functioning human brain tissue for detailed investigation by imaging, recording, and stimulation. This has resulted in slow progress in understanding and treating brain disorders. We have carved a unique research program named Stanford Brain Organogenesis that brings together expertise in neurosciences, stem cell biology, engineering, chemistry, medicine and law/ethics. We leverage powerful technologies developed at Stanford to non-invasively construct and deconstruct inaccessible stages of human brain development and function in health and brain disorders.
We believe science is a community effort, and accordingly, we plan to advance the field by training a diverse group of students, by broadly and openly sharing our technologies with laboratories around the world, and by developing ethical guidelines for this emerging field.