Publications

Preprints

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Biocompatible polymers for scalable production of human neural organoids
Genta Narazaki, Yuki Miura, Sergey D. Pavlov, Mayuri Vijay Thete, Julien G. Roth, Sungchul Shin, Sarah C. Heilshorn, Sergiu P. Pașca
bioRxiv 2022 Mar. doi: 10.1101/2022.03.18.484949

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Peer-reviewed papers

Maturation and circuit integration of transplanted human cortical organoids
Omer Revah, Felicity Gore, Kevin W. Kelley, Jimena Andersen, Noriaki Sakai, Xiaoyu Chen, Min-Yin Li, Fikri Birey, Xiao Yang, Nay L. Saw, Samuel W. Baker, Neal D. Amin, Shravanti Kulkarni, Rachana Mudipalli, Bianxiao Cui, Seiji Nishino, Gerald A. Grant, Juliet K. Knowles, Mehrdad Shamloo, John R. Huguenard, Karl Deisseroth & Sergiu P. Pașca
Nature. 2022 Oct 13; 610:319–326. doi: 10.1038/s41586-022-05277-w

Stretchable mesh microelectronics for the biointegration and stimulation of neural organoids
Thomas L. Li, Yuxin Liu, Csaba Forro, Levent Beker, Zhenan Bao, Bianxiao Cui, Sergiu P. Paşca
Biomaterials (in press)
BioRxiv 2022 Jun. doi: 10.1101/2022.06.10.495715

A nomenclature consensus for nervous system organoids and assembloids
Sergiu P. Pașca, Paola Arlotta, Helen S. Bateup, J. Gray Camp, Silvia Cappello, Fred H. Gage, Jürgen A. Knoblich, Arnold R. Kriegstein, Madeline A. Lancaster, Guo-Li Ming, Alysson R. Muotri, In-Hyun Park, Orly Reiner, Hongjun Song, Lorenz Studer, Sally Temple, Giuseppe Testa, Barbara Treutlein, Flora M. Vaccarino ​
Nature. 2022 Sept 29; 609:907–910. doi: 10.1038/s41586-022-05219-6.

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A tissue-like neurotransmitter sensor for the brain and gut
Jinxing Li, Yuxin Liu, Lei Yuan, Baibing Zhang, Estelle Spear Bishop, Kecheng Wang, Jing Tang, Yu-Qing Zheng, Wenhui Xu, Simiao Niu, Levent Beker, Thomas L Li, Gan Chen, Modupeola Diyaolu, Anne-Laure Thomas, Vittorio Mottini, Jeffrey B-H Tok, James C Y Dunn, Bianxiao Cui, Sergiu P Pașca, Yi Cui, Aida Habtezion, Xiaoke Chen, Zhenan Bao
Nature. 2022 Jun 2; 606(7912):94-101. doi: 10.1038/s41586-022-04615-2.

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Advancing models of neural development with biomaterials
Julien G Roth, Michelle S Huang, Thomas L Li, Vivian R Feig, Yuanwen Jiang, Bianxiao Cui, Henry T Greely, Zhenan Bao, Sergiu P Paşca, Sarah C Heilshorn
Nature Reviews Neuroscience. 2021 Oct; 22(10):593-615. doi: 10.1038/s41583-021-00496-y.
Free PMC article

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Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals
Jia Liu, Yoon Seok Kim, Claire E Richardson, Ariane Tom, Charu Ramakrishnan, Fikri Birey, Toru Katsumata, Shucheng Chen, Cheng Wang, Xiao Wang, Lydia-Marie Joubert, Yuanwen Jiang, Huiliang Wang, Lief E Fenno, Jeffrey B-H Tok, Sergiu P Pașca, Kang Shen, Zhenan Bao, Karl Deisseroth
Science. 2020 Mar 20; 367(6484):1372-1376. doi: 10.1126/science.aay4866.
Free PMC article

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Engineering a genetically encoded magnetic protein crystal
Thomas L Li, Zegao Wang, He You, Qunxiang Ong, Vamsi J Varanasi, Mingdong Dong, Bai Lu, Sergiu P Paşca, Bianxiao Cui
Nano Letters. 2019 Oct 9; 19(10):6955-6963. doi: 10.1021/acs.nanolett.9b02266.
Free PMC article

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Engineered materials for organoid systems
Michael J Kratochvil, Alexis J Seymour, Thomas L Li, Sergiu P Paşca, Calvin J Kuo, Sarah C Heilshorn
Nature Reviews Materials. 2019 Sep; 4(9):606-622. doi: 10.1038/s41578-019-0129-9.
Free PMC article

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The ethics of experimenting with human brain tissue
Nita A Farahany, Henry T Greely, Steven Hyman, Christof Koch, Christine Grady, Sergiu P Pașca, Nenad Sestan, Paola Arlotta, James L Bernat, Jonathan Ting, Jeantine E Lunshof, Eswar P R Iyer, Insoo Hyun, Beatrice H Capestany, George M Church, Hao Huang, Hongjun Song
Nature. 2018 Apr; 556(7702):429-432. doi: 10.1038/d41586-018-04813-x.
Free PMC article

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